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Multiple Choice

During clot formation, thrombin acts on fibrinogen to form what?

Thrombin converts soluble fibrinogen into fibrin strands that form an insoluble mesh, stabilizing the clot. It does this by cleaving fibrinopeptides from fibrinogen to create fibrin monomers, which then polymerize and, with cross-linking, become insoluble fibrin. Collagen and elastin are structural proteins of connective tissue and are not produced in the clotting process, and soluble fibrinogen is the substrate, not the product of this reaction.

Thrombin converts soluble fibrinogen into fibrin strands that form an insoluble mesh, stabilizing the clot. It does this by cleaving fibrinopeptides from fibrinogen to create fibrin monomers, which then polymerize and, with cross-linking, become insoluble fibrin. Collagen and elastin are structural proteins of connective tissue and are not produced in the clotting process, and soluble fibrinogen is the substrate, not the product of this reaction.