What are basophil granule molecules?

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Multiple Choice

What are basophil granule molecules?

Basophil granules contain mediators that drive allergic inflammation. The key molecules stored in these granules are histamine, which increases vascular permeability and promotes swelling and redness (and can constrict airway smooth muscle in allergies), and heparin, an anticoagulant that helps prevent clotting at sites of inflammation to keep immune cells flowing to the area. Other listed substances reflect products from different cells or pathways (nitric oxide and cytotoxic enzymes from cytotoxic cells, reactive oxygen species from phagocytes, and cytokines like interleukins that cells release rather than store as granule cargo). So histamine and heparin best describe basophil granule content.

Basophil granules contain mediators that drive allergic inflammation. The key molecules stored in these granules are histamine, which increases vascular permeability and promotes swelling and redness (and can constrict airway smooth muscle in allergies), and heparin, an anticoagulant that helps prevent clotting at sites of inflammation to keep immune cells flowing to the area. Other listed substances reflect products from different cells or pathways (nitric oxide and cytotoxic enzymes from cytotoxic cells, reactive oxygen species from phagocytes, and cytokines like interleukins that cells release rather than store as granule cargo). So histamine and heparin best describe basophil granule content.

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