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Multiple Choice

What are monocytes called after they enter tissues?

Monocytes circulating in blood are precursors to tissue phagocytes. When they migrate into tissues, they differentiate into macrophages, the cells that reside in tissues and actively engulf pathogens, debris, and dead cells. They also secrete cytokines that coordinate inflammation and can present processed antigens to T cells. While monocytes can give rise to dendritic cells in some environments, the common outcome once they enter most tissues is macrophage differentiation.

Monocytes circulating in blood are precursors to tissue phagocytes. When they migrate into tissues, they differentiate into macrophages, the cells that reside in tissues and actively engulf pathogens, debris, and dead cells. They also secrete cytokines that coordinate inflammation and can present processed antigens to T cells. While monocytes can give rise to dendritic cells in some environments, the common outcome once they enter most tissues is macrophage differentiation.