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Multiple Choice

Which category of adaptive immunity is mediated by B lymphocytes?

Humoral immunity is the part of adaptive immunity mediated by B lymphocytes. When B cells encounter their specific antigen, many become plasma cells that secrete antibodies into body fluids (the humors). These antibodies circulate and bind to pathogens or toxins, neutralizing them, blocking their ability to infect cells, and tagging them for destruction by other parts of the immune system (for example, by promoting opsonization and activating the complement system). Memory B cells formed during this response provide long-lasting protection against re-exposure. This differs from cell-mediated immunity, driven by T cells that attack infected host cells, and from innate immunity, which is non-specific and immediate. Autoimmunity would involve immune reactions against self-antigens, not the targeted antibody response described here.

Humoral immunity is the part of adaptive immunity mediated by B lymphocytes. When B cells encounter their specific antigen, many become plasma cells that secrete antibodies into body fluids (the humors). These antibodies circulate and bind to pathogens or toxins, neutralizing them, blocking their ability to infect cells, and tagging them for destruction by other parts of the immune system (for example, by promoting opsonization and activating the complement system). Memory B cells formed during this response provide long-lasting protection against re-exposure. This differs from cell-mediated immunity, driven by T cells that attack infected host cells, and from innate immunity, which is non-specific and immediate. Autoimmunity would involve immune reactions against self-antigens, not the targeted antibody response described here.