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Multiple Choice

Which color change in urine can indicate significant hemolysis?

When red blood cells break down rapidly, hemoglobin is released into the bloodstream. If a large amount of hemoglobin is filtered by the kidneys, it appears in the urine as hemoglobinuria, which colors the urine reddish to brown. This dark coloration signals significant intravascular hemolysis. Blue urine isn’t produced by hemolysis and might indicate a dye or pigment from medications. Clear urine means little pigment is present, which isn’t a sign of hemolysis. Yellow is the normal urine color from urochrome and doesn’t reflect hemolysis.

When red blood cells break down rapidly, hemoglobin is released into the bloodstream. If a large amount of hemoglobin is filtered by the kidneys, it appears in the urine as hemoglobinuria, which colors the urine reddish to brown. This dark coloration signals significant intravascular hemolysis.

Blue urine isn’t produced by hemolysis and might indicate a dye or pigment from medications. Clear urine means little pigment is present, which isn’t a sign of hemolysis. Yellow is the normal urine color from urochrome and doesn’t reflect hemolysis.