Which four types of WBCs are part of the body's non-specific defenses?

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Non-specific defenses rely on innate immune cells that respond quickly to a wide range of pathogens. The four white blood cell types that participate most directly in this rapid, non-specific defense are neutrophils, eosinophils, basophils, and monocytes. Neutrophils are the first responders and perform phagocytosis to destroy invaders. Monocytes circulate in the blood and, when they migrate into tissues, become macrophages that also phagocytose pathogens and debris. Eosinophils help combat parasites and modulate inflammatory responses, while basophils release histamine and other mediators that promote inflammation and recruit more immune cells. Lymphocytes, on the other hand, are primarily linked to adaptive immunity, providing targeted, memory-based responses rather than broad, immediate defense. So those four innate-cell types—neutrophils, eosinophils, basophils, and monocytes—best fit the non-specific defenses.